Looking for Post-Doctoral Fellow in Immunology to work on Regulatory B cells
Background: Immunology or related fields (PhD or MD with relevant experience)
Location: University of Pittsburgh School of Medicine
Description: Post-Doctoral Fellow needed to spearhead an NIH-funded project on REGULATORY B CELLS. A remarkable potent subset of ProB cells found in the bone marrow contains Breg precursors that can protect mice from autoimmunity (NOD, EAE) and prevent allograft rejection upon transfer of only ~50,000 cells to wild-type mice (Korniotis, Nat Commun 2016). This work provides the first-ever evidence of a true Breg lineage. We will further characterize these cells and their progeny to identify genetic control of this lineage and their relationship to recently described TIM-1+B cells (Xiao Cell reports 2020) through RNAseq and ATACseq and further identify their mechanism of action in autoimmune and transplant models.
Salary commensurate with level of experience.
The University of Pittsburgh is an Affirmative Action/Equal Opportunity Employer and values equality of opportunity, human disnity and diversity, EOE, including disability/vets.
Please send inquiries with C.V. to David Rothstein: firstname.lastname@example.org